The Human Genome Project And Encyclopedia Of Dna Elements

Understanding our life as we know it must start at the basics with our own DNA. DNA is the building blocks for all life, so to understand life we must analyze the mechanism of genetics. Projects like the Human Genome project and Encyclopedia of DNA elements (ENCODE) analyzes DNA to give society an interpretation of what the building code is and means. Our genetic code holds coding and non-coding sequences, at first researchers focused solely on coding DNA for it carried the function and means to life. The other non-coding was for years considered to be junk but in this review it will be highlighted by the example of Transposable elements that this so called useless DNA holds many secrets and keys to life. It is now recognized that genomic changes are influenced by transposable elements which has changed the way it is thought how genomes evolve and work. DNA Introduction Deoxyribonucleic acid, the building blocks for about all living creatures on Earth. Almost every cell in the human body shares the same DNA. Since DNA is practically the blueprint for living organisms, understanding the blueprint is crucial to a better understanding of the phenomena of our own bodies and the relationship between genetic variation and disease risk hopefully leading to the cure of many diseases, the prevention of harmful mutations, and possibly an explanation to our creation. This DNA is all the information for one’s body and is stored as a code with 4 chemical bases. As seen in theShow MoreRelatedEssay on The Human Genome Project1437 Words   |  6 Pagesdeeply in our body is the complex biological story. The Human Genome Project is the exploration of this intricate yet crucial storyline. The Genome is a complete set of genes that make up an organism. Genes are made up of DNA (deoxynucleic acid) which subsequently is made up of long paired strands. These paire d strands attach in a specific manner, for example, Adenine (A) attaches itself to Thymine (T) and Cytosine(C) to Guanine (G). The genome is the perplexing key in instructing cells to do theirRead MoreHow The Firm Strategy Affect The Emergence Of The Genomic Industry?1489 Words   |  6 Pagesanalysis of an individual’s genome. The industry can create a new avenue of approach in which it may profit through the production of tailored products and insights through the study of individual genome. This will also allow for the development of new technology and growth. Because of the necessity of a great quantity of diverse phenotypic and genomic data, this industry firm strategy will also consider genome databases and direct to consumer (DTC) genetic testing. Genome databases will give companiesRead MoreBiological Networks And The Biomedical And Genomic Fields962 Words   |  4 Pagesare ENCODE (Encyclopedia of DNA Elements) and TCGA (The Cancer Genome Atlas). The ENCODE project14, 15 was launched to identify all functional elements in the human genome - regions of transcription, transcription factor association, chromatin structure and histone modification. The ENCODE project has generated more than 6000 genomic datasets from ChIP-seq, RNA-seq, DNase-seq, shRNA knockdown followed by RNA-seq (The ENCODE Project Consortium, 2015). The pilot phase of the ENCODE project involved 440Read MoreThe Encyclopedia Of Dna Elements2407 Words   |  10 Pages The Encyclopedia of DNA Elements (ENCODE) is a project designed to compare and contrast the repertoire of RNAs produced by the human cells and cross verify with other methods like NGS. After a five year start-up since the beginning of the ENCODE project just 1% of the human genome has been observed and what was achieved was just the confirmation of the results of previous studies. RNA has functions of coding, regulation, decoding, and gene expression. RNA highlights the sequential output from genomesRead MoreGenome Decoding: A Review of Three Articles1724 Words   |  7 Pagesthen states the reason why this newspaper gave a better version of the covered story among others based on the tendency (context), the information giving, and the supported arguments that this newspaper have. Genome Decoding: A review of three articles on the subject Introduction Genome Decoding is one of the most recent tantalizing scientific discoveries that have recently appeared in the news. Scientists have discovered that the 20,000 genes that do not code for proteins (and were, thereforeRead MoreAnnotated Bibliography On The Rna Profiling1999 Words   |  8 Pagesthe genome functions also. These observation are taken up together to form and define the functions and description related to genes (Bell, 2004). This observation tells about the range of expression and localization. As the technology is been improving day by day for the RNA profiling and the type of isolation made by the cells , the number of RNA has grown and has increase the biological function in an fast and immediate rate. The ENCODE project also known as the Encyclopedia of DNA element projectRead MoreCharacteristics Of The Functional Area Of Human Genome2127 Words   |  9 Pagessegment of human genome is formed of protein sequences while some of the non coded DNA indicates biologica l functions. Along with the coding of genomes, they are also consisted of sequence which is transcript into RNA like tRNA, rRNA .New challenges of these sequences in the non protein are most prevalent. They are known to identify the functional area in the human genome which is studied by (ENCODE) project. The characteristics which are acting upon the regulatory variations amongst the human beingsRead MoreAnnotated Bibliography On The Landscape Of Transcription2715 Words   |  11 PagesLANDSCAPE OF TRANSCRIPTION IN HUMAN CELLS INTRODUCTION The Encyclopedia of DNA Elements (ENCODE) is a project designed to compare and contrast the repertoire of RNAs produced by the human cells and cross verify with other methods like NGS. After a five year start-up since the beginning of the ENCODE project just 1% of the human genome has been observed and what was achieved was just the confirmation of the results of previous studies. RNA has functions of coding, regulation, decoding, and geneRead MoreThe Encyclopedia Of Dna Elements2709 Words   |  11 PagesINTRODUCTION The Encyclopedia of DNA Elements (ENCODE) is a project designed to compare and contrast the repertoire of RNAs produced by the human cells and cross verify with other methods like NGS. After a five year start-up since the beginning of the ENCODE project just 1% of the human genome has been observed and what was achieved was just the confirmation of the results of previous studies. RNA has functions of coding, regulation, decoding, and gene expression. RNA highlights the sequential outputRead MoreSilico Characterization Of The Association Between Rs12670798 And Ldl Cholesterol2868 Words   |  12 PagesIntroduction Complex diseases are caused by multiple genetic and environmental factors working in combination with each other and thus, it is difficult to characterise the contribution of any one factor to the disease1. However, the widespread adoption of genome-wide association studies (GWAS) has greatly accelerated the rate at which these factors are discovered and characterised. These studies genotype individuals with different phenotypes (for example, those who are affected or unaffected by a complex